Regulatory
pLux

Part:BBa_K2267029:Design

Designed by: DENG, TINGYUE   Group: iGEM17_TUST_China   (2017-10-25)


Plux1


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Quorum-sensing bacteria such as Vibrio fischeri, are able to detect their own population density and regulate their growth accordingly.Using the luxI/luxR quorum-sensing system, synthetic biologists have designed a large number of devices in prokaryotic microorganisms.Naturally, high performance is required from such devices, and this includes reliability and sensitivity. Hence, with the goal to improve the properties of population-density switches, we design an ultrasensitive responses base. https://parts.igem.org/Part:BBa_R0062 use Point mutation

Source

https://parts.igem.org/Part:BBa_R0062

References

Rational design of an ultrasensitive quorum-sensing switch